An Efficient Procedure for the Regiosele
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Derek H.R. Barton; Jieping Zhu
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Article
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1992
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Elsevier Science
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French
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Nucleophilic ring opening of isopropylidene ketals by trimethylaluminum is described. This reagent offers a new method for selective monoprotection of 12-diols. The regioselectivity of this reaction was studied with simple diols and with carbohydrates. Selective protection of a specific hydroxy gro