A convenient procedure for converting organic thiols into ethyldithio derivatives

✍ Scribed by Nimal Jayasuriya; Steven L. Regen

• Publisher: Elsevier Science
• Year: 1992
• Tongue: French
• Weight: 124 KB
• Volume: 33
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(00)93965-0

✦ Synopsis

A procedure has been devl\ed for convertmg orgamc thlols into ethyldlthlo denvanves that requires only filtration dnd solvent ev'lpordtlon stepa for product lsolntlon Dunng the course of our studlec deahng the synthesis of dlsulftde-based polymenzed hposomek we hdd routine need for protectmg certain thlol-sub%tltuted organic acids * While standard hterature procedures for converting the thlol moiety Into the corresponchng ethyldlthlo denvatlve proved sdtlsfactory for this purpose,3*4 we sought a more convenient method thdt could be camed out effectively under tmld condltlon?, and would allow products to be lqolated more readily 5 Here we descnbe such a procedure