A convenient one-pot synthesis of 1,2-azaphospholanium salts

✍ Scribed by Inga M. Aladzheva; Dmitrii I. Lobanov; Ol'ga V. Bykhovskaya; Pavel V. Petrovskii; Konstantin A. Lyssenko; Tatyana A. Mastryukova

• Publisher: John Wiley and Sons
• Year: 2003
• Tongue: English
• Weight: 120 KB
• Volume: 14
• Category: Article
• ISSN: 1042-7163
• DOI: 10.1002/hc.10209

✦ Synopsis

Abstract

A novel facile one‐pot synthesis of the 1,2‐azaphospholanes by intramolecular alkylation of 3‐halopropyl amides of tricoordinate phosphorus has been suggested. Using this method, a series of the differently N‐substituted 1,2‐azaphospholanium salts were synthesized. 3‐Aminopropylphosphine oxides were obtained by hydrolysis of the salts. A probable mechanism of the 1,2‐azaphospholanium salts formation is discussed. © 2003 Wiley Periodicals, Inc. Heteroatom Chem 14:596–602, 2003; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.10209