One of the drug specific parameters needed in physiologically based pharmacokinetic (PBPK) models is the tissue to plasma drug concentration ratios (K(p) values). The aim of this study was to develop an empirical method for predicting K(p) values using a preclinically determined in vivo volume of di
✦ LIBER ✦
A convenient method to measure blood–plasma concentration ratio using routine plasma collection in in vivo pharmacokinetic studies
✍ Scribed by Leonid M. Berezhkovskiy; Xiaolin Zhang; Jonathan Cheong
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 116 KB
- Volume
- 100
- Category
- Article
- ISSN
- 0022-3549
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