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A convenient method for the synthesis of six-membered heterocyclic enaminones

✍ Scribed by Pilar Puebla; Zoila Honores; Manuel Medarde; Esther Caballero; Arturo San Feliciano; Lourdes Morán

Book ID: 102341385
Publisher: Journal of Heterocyclic Chemistry
Year: 1999
Tongue: English
Weight: 229 KB
Volume: 36
Category: Article
ISSN: 0022-152X
DOI: 10.1002/jhet.5570360445

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✦ Synopsis

Abstract

Enaminones are widely employed in the synthesis of heterocycles, however heterocyclic enaminones and their use in the synthesis of more complex systems have been less studied. The reaction between 4‐chloroacetylacetate and aliphatic or aromatic 1,2‐aminoalcohols, 1,2‐aminothiols or 1,2‐diamines, yields in one pot a six‐membered 1,4‐heterocyclic system containing the enaminone moiety.

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