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A convenient method for the synthesis of 4,4-diarylbut-1-enes via the successive allylation of aromatic aldehydes and the Friedel–Crafts alkylation reaction of aromatic nucleophiles with the intermediary benzyl silyl ethers using HfCl4 or Cl2Si(OTf)2

✍ Scribed by Isamu Shiina; Masahiko Suzuki; Kazutoshi Yokoyama


Publisher
Elsevier Science
Year
2002
Tongue
French
Weight
95 KB
Volume
43
Category
Article
ISSN
0040-4039

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📜 SIMILAR VOLUMES


The catalytic Friedel–Crafts alkylation
✍ Isamu Shiina; Masahiko Suzuki 📂 Article 📅 2002 🏛 Elsevier Science 🌐 French ⚖ 126 KB

The Friedel-Crafts alkylation reaction of various aromatic compounds with benzyl or allyl silyl ethers is effectively promoted under mild reaction conditions using Lewis acid catalysts. A mixture of the desired phenyltolylmethanes is obtained in 80% yield from toluene with benzyl dimethylsilyl or tr