A Convenient Method for the Preparation of N -Aryl and N -Alkyl- O -Methyl Hydroxylamines
β Scribed by Santos, Paulo F.; Lobo, Ana M.; Prabhakar, Sundaresan
- Book ID
- 121491705
- Publisher
- Taylor and Francis Group
- Year
- 1995
- Tongue
- English
- Weight
- 345 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0039-7911
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π SIMILAR VOLUMES
A convenient synthesis of N-(aminoalkylacyl)sulfonamides from CBZ potected glycine, B-alanine and GABA is described. During an investigation into the preparation of new pharmacologically active amino acid analogs we wished to explore the pharmacological properties of compounds which bore both an equ
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Abstruct : Treatment of &,P(O)Cl with MesSiNI-IOSiM~ gives Pr$P(0)NHOSiMes. which is desilylated by methanol giving P&P(O)NHOH. The 0-p-nitrobenz.enesulphonyI derivative of this rearranges with KOBu' in BuYIH, an isopropyl group migrating from P to N and the phosphonamidate R'P(O)(OBu?NIIpi being fo