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A Convenient Method for the Preparation of Highly Substituted Pyrimidines: Synthesis of Tri- and Tetra-Substituted Pyrimidines from 1,3-Dicarbonyl Compounds and N,N,N′-Tris-(trimethylsilyl)amidines.

✍ Scribed by Usha Ghosh; John A. Katzenellenbogen


Publisher
John Wiley and Sons
Year
2003
Weight
125 KB
Volume
34
Category
Article
ISSN
0931-7597

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A convenient method for the preparation
✍ Usha Ghosh; John A. Katzenellenbogen 📂 Article 📅 2002 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 62 KB

## Abstract A modification of the Pinner pyrimidine synthesis has been developed that utilizes trimethylsilyl amidines and results in greatly improved yield of highly substituted pyrimidines.