## Abstract A simple method is described to label cholesterol with tritium. Cholesterol was first oxidized to 5‐cholesten‐3‐one (2) which was then purified by HPLC. Its structure was established by electron impact (EI) mass spectrometry and ^1^H‐NMR spectroscopy. The ketone (2) was reduced with NaB
A Convenient Method for labelling biologically interesting Carboxylic Acids with Tritium
✍ Scribed by BUU-HOÏ, N. P.
- Book ID
- 109594242
- Publisher
- Nature Publishing Group
- Year
- 1957
- Tongue
- English
- Weight
- 231 KB
- Volume
- 180
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/180385a0
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## Abstract The specific tritium labelling of beta‐adrenoceptor antagonists of the general structure ArOCH~2~CH(OH)CH~2~NHR is described. The tritium label is introduced in the 2‐position in the aminohydroxypropoxy side‐chain starting from ArOCH, an intermediate in the synthesis of the unlabelled c
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