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A convenient iodonium-ion-assisted synthesis of an immunologically active tetrameric β (1→5)-linked D-galactofuranoside from the extracellular polysaccharide of Aspergillus and Penicillium species

✍ Scribed by H. M. Zuurmond; P. A. M. van der Klein; G. H. Veeneman; J. H. van Boom


Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
489 KB
Volume
109
Category
Article
ISSN
0165-0513

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✦ Synopsis


Abstract

The non‐terminal glycosyl donor, ethyl 2,3‐di‐O‐benzoyl‐5‐O‐(chloroacetyl)‐6‐O‐pivaloyl‐1‐thio‐α‐D‐galactofuranoside, could be used, with the promoter N‐iodosuccinimide and catalytic trifluoromethanesulfonic acid, for the preparation of β‐D‐Gal__f__‐(1→5)‐β‐D‐Gal__f__‐(1→5)‐β‐D‐Gal__f__‐(1→5)‐β‐D‐Gal__f__‐OMe.