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A convenient deoxygenation of α,β-epoxy ketones to enones

✍ Scribed by Reginaldo B. dos Santos; Timothy John Brocksom; Ursula Brocksom

Publisher
Elsevier Science
Year
1997
Tongue
French
Weight
164 KB
Volume
38
Category
Article
ISSN
0040-4039

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✦ Synopsis

A new and efficient methodology for the deoxygenation of ct,13-epoxy ketones to enones has been developed, using aminoiminomethanesulfinic acid (thiourea dioxide) as the reducing agent under phase transfer conditions. The epoxides of mesityl oxide, isophorone, (-)-carvone, (+)-6-methyl-carvone, (+)-6-ethyl-carvone and (-)-rnyrtenal, were converted into their respectives enones in good to excellent yields.

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