A Convenient and Environmentally Benign Method of Reducing Aryl Ketones or Aldehydes by Zinc Powder in an Aqueous Alkaline Solution

✍ Scribed by Chao-Zhi Zhang; Hui Yang; De-Lin Wu; Guo-Yuan Lu

• Publisher: John Wiley and Sons
• Year: 2007
• Tongue: English
• Weight: 220 KB
• Volume: 25
• Category: Article
• ISSN: 0256-7660
• DOI: 10.1002/cjoc.200790122

✦ Synopsis

Abstract

A convenient and environmentally benign method for reducing the carbonyl group in hydroxy‐ and amino‐ 9,10‐anthracenediones, ortho (or para) acyl phenols and acyl anilines to a methylene group by zinc powder in an aqueous sodium hydroxide solution was reported. Based on theoretical calculations using the density functional theory (DFT), the mechanism of these reduction reactions was postulated. This mechanism can be applied to help predicting the reduced products of aryl ketones (or aldehydes) in an alkaline solution.