Imidazolidine-2,4-dione was chemoselectively N-alkylated at the imidic NH with several 2-(3,4-dihydro-1-naphthalenyl)ethyl-4-methylphenylsulphonates to give the corresponding imides for the first time which on selective reduction at one of the carbonyl groups followed by cyclization in PPA gave the
A Convenient and Efficient Synthesis of SLeX Analogs
โ Scribed by Hayashi, Masaji; Tanaka, Masashi; Itoh, Masanori; Miyauchi, Hiroshi
- Book ID
- 126133653
- Publisher
- American Chemical Society
- Year
- 1996
- Tongue
- English
- Weight
- 357 KB
- Volume
- 61
- Category
- Article
- ISSN
- 0022-3263
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
A general one-pot synthesis is described for the preparation, in good overall yields, of phosphinopeptides as building blocks for peptide synthesis in the field of new enzyme inhibitors. This method, consisting of the addition of alkyl hypophosphites to imines and then in the Michael-addition of the
The recently isolated marine natural product pseudoceratidine (1) has been synthesized from 2-trichloroacetylpyrrole. Bromination in the 4-and 5-position followed by nucleophilic displacement of the trichloromethyl group with spermidine gave 1 in 79 g yield. The procedure is general and can easily b