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A constitutive mutation, phoT, of the repressible acid phosphatase synthesis with inability to transport inorganic phosphate in Saccharomyces cerevisiae

✍ Scribed by Ueda, Yoshinami ;Oshima, Yasuji


Publisher
Springer
Year
1975
Tongue
English
Weight
283 KB
Volume
136
Category
Article
ISSN
0026-8925

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✦ Synopsis


Wild-type cells of Saccharomyces cerevisiae cultivated in low-Pi medium actively accumulate inorganic phosphate (Pi), while the same cells cultivated in high-Pi medium do not. A recessive constitutive mutant (phoT), for repressible acid phosphatase (EC 3.1.3.2) synthesis, is described. It shows severely reduced potency of Pi uptake, while the recessive constitutive mutants, phoR and phoU, in the same system show wild-type potency as.