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A Concise Total Synthesis of ( R )-Puraquinonic Acid

โœ Scribed by Tiong, Erica A.; Rivalti, Daniel; Williams, Benjamin M.; Gleason, James L.


Book ID
118748607
Publisher
John Wiley and Sons
Year
2013
Tongue
English
Weight
500 KB
Volume
52
Category
Article
ISSN
0044-8249

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2-Methyl-1,4-benzenediol (10) was acylated with a-chloroisobutyroyl chloride and converted by treatment with AlCl 3 into the indanone derivative 12, which was elaborated into the substituted indane acid 24. Oxidation then afforded racemic puraquinonic acid.

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