## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
A Concise Synthesis of (+)-Cerulenin from a Chiral Oxiranyllithium
β Scribed by Mani, Neelakandha S.; Townsend, Craig A.
- Book ID
- 126275232
- Publisher
- American Chemical Society
- Year
- 1997
- Tongue
- English
- Weight
- 214 KB
- Volume
- 62
- Category
- Article
- ISSN
- 0022-3263
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π SIMILAR VOLUMES
The antifungal antibiotic, cerulenin 3 was isolated from the culture filtrate of Cephalosporium caerulens, 1 and shown to inhibit lipid biosynthesis of Escherichia coli by irreversibly binding P-ketoacyl-acyl carrier protein synthetase, the enzyme which catalyzes the acylation of a malonyl thioester
lJ-g&cane ban AULU~ cu a ctid byrdhon in a total 6ynthe.k 06 the &?gd me..&bo.GZe The fungal metabolite cerulenin 14 possesses a very interesting spectrum of biological acti-vities' and three total syntheses of dl-cerulenin have been reported\*. On the other hand, two