✦ LIBER ✦

A concise synthesis of 3-hydroxyindole-2-carboxylates by a modified Baeyer–Villiger oxidation

✍ Scribed by Zachary L. Hickman; Claudio F. Sturino; Nicolas Lachance

Book ID: 104211007
Publisher: Elsevier Science
Year: 2000
Tongue: French
Weight: 87 KB
Volume: 41
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)01456-8

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✦ Synopsis

Indole-2-carboxylates are converted in good yields to 3-hydroxyindole-2-carboxylates by use of a Vilsmeier-Haack/Baeyer-Villiger reaction sequence. A systematic examination of the various indole substituents revealed this route to be general in scope.

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