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A concise synthesis of 1-(3-hydroxymethyl-4,5-dihydroxyphenyl)-2-tert-butylamino-ethanol (5-hydroxyalbuterol)

✍ Scribed by Nathan K Yee; Larry J Nummy; Gregory P Roth


Book ID
108039061
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
114 KB
Volume
6
Category
Article
ISSN
0960-894X

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Synthesis of 5-substituted 2-(2,4-dihydr
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## Abstract magnified image One‐stage synthesis of 5‐substituted (alkyl, aryl, heteroaryl, arylalkyl, heteroalkyl, alkoxy‐, aryloxy)‐2‐(2,4‐dihydroxyphenyl)‐1,3,4‐thiadiazoles is described. The compounds were prepared by the reaction of sulfinyl‐bis(2,4‐dihydroxythiobenzoyl) (STB) with hydrazides