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A Concise Sultone Route to Highly Oxygenated 1,10-seco-Eudesmanolides — Enantioselective Total Synthesis of the Antileukemic Sesquiterpene Lactones (-)-Eriolanin (Ia) and (-)-Eriolangin (Ib).

✍ Scribed by Joern Merten; Andre Hennig; Pia Schwab; Roland Froehlich; Sergey V. Tokalov; Herwig O. Gutzeit; Peter Metz

Publisher
John Wiley and Sons
Year
2006
Weight
11 KB
Volume
37
Category
Article
ISSN
0931-7597

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📜 SIMILAR VOLUMES

A Concise Sultone Route to Highly Oxygen
A Concise Sultone Route to Highly Oxygenated 1,10-seco-Eudesmanolides – Enantioselective Total Synthesis of the Antileukemic Sesquiterpene Lactones(–)-Eriolanin and (–)-Eriolangin
✍ Jörn Merten; André Hennig; Pia Schwab; Roland Fröhlich; Sergey V. Tokalov; Herwi 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 339 KB

## Abstract Using a sultone as the key intermediate, the first enantioselective total synthesis of the antileukemic 1,10‐__seco__‐eudesmanolides (–)‐eriolanin (**1**) and (–)‐eriolangin (**2**) was achieved, which also established the hitherto unknown absolute configuration of these sesquiterpene l