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A Concise Semi-Synthetic Approach to Betulinic Acid from Betulin

✍ Scribed by Kim, Darrick S. H. L.; Chen, Zhidong; Nguyen, van Tuyen; Pezzuto, John M.; Qiu, Shengxiang; Lu, Zhi-Zhen

Book ID
111903123
Publisher
Taylor and Francis Group
Year
1997
Tongue
English
Weight
260 KB
Volume
27
Category
Article
ISSN
0039-7911

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πŸ“œ SIMILAR VOLUMES

A semi-synthetic approach to olefinic an
A semi-synthetic approach to olefinic analogs of amino acid one (MeBMT) in cyclosporin A
✍ Sang B. Park; G.Patrick Meier πŸ“‚ Article πŸ“… 1989 πŸ› Elsevier Science 🌐 French βš– 274 KB

The syntheses of four olefinic analogs of Cyclosporin A at amino acid one (MeBMT), a residue critical for the Cyclophilin binding domain, are reported. The synthetic process is a rapid, general, semi-synthetic sequence involving oxidative degradation of the olefinic sidechain followed by a Wittig ol