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A Concise Route to the Core Pentasaccharide of N-Linked Glycoproteins.

✍ Scribed by Vadim Y. Dudkin; Justin S. Miller; Samuel J. Danishefsky


Publisher
John Wiley and Sons
Year
2003
Weight
56 KB
Volume
34
Category
Article
ISSN
0931-7597

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ChemInform Abstract: A Highly Convergent
✍ S. J. DANISHEFSKY; S. HU; P. F. CIRILLO; M. ECKHARDT; P. H. SEEBERGER πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 30 KB πŸ‘ 1 views

A Highly Convergent Total Synthetic Route to Glycopeptides Carrying a High-Mannose Core Pentasaccharide Domain N-Linked to a Natural Peptide Motif. -A novel and efficient synthesis of the pentasaccharide portion of asparagine-linked glycoproteins is established. Coupling of disaccharide acceptor gl