A concise and improved synthesis of (+)-eleutherin, (+)-allo-eleutherin and a formal synthesis of (+)-nocardione B
โ Scribed by Rodney A. Fernandes; Vijay P. Chavan; Sandip V. Mulay
- Book ID
- 108284663
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- English
- Weight
- 509 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0957-4166
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## Abstract Enantioselective synthesis of deoxy analogues of pyranonaphthoquinone antibiotics (+)โnanomycin A methyl ester, (+)โeleutherin, (+)โalloโeleutherin, and (+)โthysanone was achieved in good overall yield with high enantioโ and diastereoselectivity from the common intermediate (__R__)โ3โ(2
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a โFull Textโ option. The original article is trackable v
1H-Naphtho[2,3-c]pyran-5,10-dione derivatives, including a natural product (pentalongin), were generally synthesized in one-pot using a tandem conjugate addition-cyclization sequence between 2-(1-hydroxyalkyl)-1,4naphthoquinones and enamines (or imines). The utility of this method was demonstrated i