A computer simulation analysis of the accuracy of partial genome sequencing and restriction fragment analysis in estimating genetic relationships: an application to papillomavirus DNA sequences

A computer simulation analysis of the ac

A computer simulation analysis of the accuracy of partial genome sequencing and restriction fragment analysis in the reconstruction of phylogenetic relationships

✍ Baozhen Qiao; Tony L. Goldberg; Gary J. Olsen; Ronald M. Weigel 📂 Article 📅 2006 🏛 Elsevier Science 🌐 English ⚖ 301 KB

Partial genome sequencing (PGS) and restriction fragment analysis (RFA) are used frequently in molecular epidemiologic investigations. The relative accuracy of PGS and RFA in phylogenetic reconstruction has not been assessed. In this study, 32 model phylogenetic trees with 16 extant lineages were ge