A computer program for tracing radioactivity in complex metabolic systems

✍ Scribed by Michael Haut; Sandra Basickes

• Publisher: Elsevier Science
• Year: 1967
• Tongue: English
• Weight: 333 KB
• Volume: 1
• Category: Article
• ISSN: 0010-4809
• DOI: 10.1016/0010-4809(67)90012-2

✦ Synopsis

A program is described to determine the labeling pattern following addition to an unlabeled biochemical system of a labeled compound. Input for this program consists of a set of equations describing the unlabeled system, and a specifically labeled compound. A computation consists of a series of passes, in which all the input equations are executed in order, using all possible labeling combinations of the reacting substances. The output consists of all the new equations (i.e., equations containing new labeled compounds, or new types of equations forming labeled compounds already present resulting from each pass. The application of this program to the study of highly interconnected metabolic systems is discussed.