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A computer program for life table regression analysis with time-dependent covariates

✍ Scribed by Peter Peduzzi; Theodore Holford; Robert Hardy

Publisher
Elsevier Science
Year
1979
Weight
557 KB
Volume
9
Category
Article
ISSN
0010-468X

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✦ Synopsis

This paper presents a computer program for analyzing time-dependent covariables in survival studies by the life table regression model described by Holford [ 3 ]. Basically, life table regression incorporates the elements of regression and the life table into a single model. Regression parameters are estimated by the method of maximum likelihood using the Newton-Raphson iterative procedure. The program provides two methods for testing hypotheses concerning regression coefficients, namely the standard normal deviate test and a Wald statistic based on the first and second derivatives of the log likelihood. Residual plots are provided to assess the fit of the model to the data. Life tables Regression Time-dependent Survival analysis Covariates

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