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A computational method for detecting copy number variations using scale-space filtering

โœ Scribed by Jongkeun Lee, Unjoo Lee, Baeksop Kim, Jeehee Yoon


Book ID
120675279
Publisher
BioMed Central
Year
2013
Tongue
English
Weight
894 KB
Volume
14
Category
Article
ISSN
1471-2105

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We report the development of a real-time Invader assay combined with multiplex PCR (mPCR-RETINA), an SNP-based approach that can measure the allelic ratio in copy number variation (CNV) regions of a genome. RETINA monitors the real-time fluorescence intensity of each allele during the Invader assay