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A comprehensive study to determine heterogeneity of autosomal recessive nonsyndromic hearing loss in Iran

✍ Scribed by Mojgan Babanejad; Zohreh Fattahi; Niloofar Bazazzadegan; Carla Nishimura; Nicole Meyer; Nooshin Nikzat; Elahe Sohrabi; Amin Najmabadi; Peyman Jamali; Farkhonde Habibi; Richard J.H. Smith; Kimia Kahrizi; Hossein Najmabadi


Book ID
115549403
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
207 KB
Volume
158A
Category
Article
ISSN
1552-4825

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Identification of mutations in the conne
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Mutations in the Cx26 gene have been shown to cause autosomal recessive nonsyndromic hearing loss (ARNSHL) at the DFNB1 locus on chromosome 13q12. Using direct sequencing, we screened the Cx26 coding region of affected and nonaffected members from seven ARNSHL families either linked to the DFNB1 loc