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A Comprehensive Docking Study on the Selectivity of Binding of Aromatic Compounds to Proteins

✍ Scribed by Hetenyi, C.; Maran, U.; Karelson, M.


Book ID
126444555
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
225 KB
Volume
43
Category
Article
ISSN
0095-2338

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## Abstract Enzymes with ribonucleolytic activity play a pivotal role in gene expression and cellular homeostasis by altering the levels of cellular RNA. Ribonuclease A has been the most well studied of such enzymes whose histidine residues (His^12^ and His^119^) play a crucial role in the catalyti