A comprehensive approach to the photochemical synthesis of bioactive compounds by the reaction of oxazolidine, thiazolidine and pyrazolidine derivatives with indol-2,3-diones
✍ Scribed by I. Sharma; A. Saxena; C. K. Ojha; P. Pardasani; R. T. Pardasani; T. Mukherjee
- Book ID
- 110644628
- Publisher
- Indian Academy of Sciences,Royal Society of Chemistry
- Year
- 2002
- Tongue
- English
- Weight
- 56 KB
- Volume
- 114
- Category
- Article
- ISSN
- 0253-4134
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The enolate of 4-N-(tert-butyloxycarbonyl)aminobutyro-7-lacto~e 9 reacted with 2-bromo-1methylindole-3-carboxaldehyde it, the presence of stannic chloride to give the product of aldol condensation 16. Deprotection and dehydration of the latter with trifluoroacetic' acid and dimethyl sulfide followed
## Abstract Triphenylphosphine (TPP) has been utilized as a novel and efficient catalyst for the Knoevenagel condensation of indole‐3‐carboxaldehydes **1(a–e)**, 1‐methyl‐1H‐indole‐3‐carboxaldehydes **4(a–e)**, and 1‐ethyl‐1H‐indole‐3‐carboxaldehydes **6(a–e)** with the active methylene compound, t