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A component of the transcriptional represser MeCP1 shares a motif with DNA methyltransferase and HRX proteins

✍ Scribed by Cross, Sally H.; Meehan, Richard R.; Nan, Xinsheng; Bird, Adrian


Book ID
109916523
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
598 KB
Volume
16
Category
Article
ISSN
1061-4036

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The small transcriptional repressor CopG protein (45 amino acids) encoded by the streptococcal plasmid pMV158 was purified to near homogeneity. Gel filtration chromatography and analytical ultracentrifugation showed that the native protein is a spherical dimer of identical subunits. Circular dichroi