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A Complex Proinflammatory Role for Peripheral Monocytes in Alzheimer's Disease

✍ Scribed by Saresella, Marina (author);Marventano, Ivana (author);Calabrese, Elena (author);Piancone, Federica (author);Rainone, Veronica (author);Gatti, Andrea (author);Alberoni, Margherita (author);Nemni, Raffaello (author);Clerici, Mario (author)

Book ID
120981339
Publisher
IOS Press
Year
2013
Tongue
English
Weight
486 KB
Volume
38
Category
Article
ISSN
1387-2877

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## Abstract Alzheimer's disease (AD) is a dementing neurodegenerative disorder without a cure. The abnormal parenchymal accumulation of β‐amyloid (AΞ²) is associated with inflammatory reactions involving microglia and astrocytes. Increased levels of AΞ² and AΞ² deposition in the brain are thought to c