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A complex polymorphic region in the brain-derived neurotrophic factor (BDNF) gene confers susceptibility to bipolar disorder and affects transcriptional activity

โœ Scribed by Okada, T; Hashimoto, R; Numakawa, T; Iijima, Y; Kosuga, A; Tatsumi, M; Kamijima, K; Kato, T; Kunugi, H


Book ID
110060101
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
153 KB
Volume
11
Category
Article
ISSN
1359-4184

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## Abstract Recent studies have indicated that the brainโ€derived neurotrophic factor (__BDNF__) gene is involved in the etiology of bipolar disorder (BPD). Two familyโ€based association studies showed that the Val allele of the functional polymorphism Val66Met in the __BDNF__ gene is associated with