A comparison of a mixture likelihood met
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Hojin Moon; Hongshik Ahn; Ralph L. Kodell; Bruce A. Pearce
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Article
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1999
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Elsevier Science
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English
⚖ 226 KB
Both a mixture likelihood method and the EM algorithm are implemented to estimate the time-toonset-of and the time-to-death-from the tumor of interest in animal carcinogenicity studies. Both methods are implemented using Box's Complex Method for ÿnding the maximum likelihood estimates of parameters