A comparison of two methods of estimating a common risk difference in a stratified analysis of a multicenter clinical trial
β Scribed by Thomas W. O'Gorman; Robert F. Woolson; Michael P. Jones
- Book ID
- 113297930
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 897 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0197-2456
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π SIMILAR VOLUMES
When a clinical trial is conducted at more than one centre it is likely that the true treatment effect will not be identical at each centre. In other words there will be some degree of treatment-by-centre interaction. A number of alternative approaches for dealing with this have been suggested in th
Using the Monte Carlo simulation, we estimated the statistical power and Type I error rates of ΓΏve procedures for testing the signiΓΏcance of a common risk di erence in a set of independent 2 Γ 2 tables. It was found that the unweighted procedure for testing the signiΓΏcance of a common risk di erence