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A comparison of the β1–selectivity of conventional metoprolol and metoprolol CR during exercise in healthy volunteers

✍ Scribed by S. Akhlaghi; S. R. J. Maxwell; M. J. Kendall; B. Hughes; P. Greenhaff


Book ID
114738391
Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
574 KB
Volume
18
Category
Article
ISSN
0269-4727

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We have studied a controlled-release formulation containing metoprolol 100 mg and hydrochlorothiazide 12.5 mg. We compared the pharmacokinetics of both substances and the pharmacodynamics of metoprolol with those of a conventional combination tablet. The controlled-release formulation gave less vari