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A comparison of the roles of p53 mutation and AraC inhibition in the enhancement of bleomycin-induced chromatid aberrations in mouse and human cells

โœ Scribed by Theresa Allio; E.Maria Donner; R.Julian Preston


Book ID
114072654
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
120 KB
Volume
447
Category
Article
ISSN
0027-5107

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The relative contribution to development of hepatocellular carcinoma of the mouse equivalent to the human p53ser249 mutation, found in human hepatocellular carcinoma associated with aflatoxin (AFB1) exposure, is compared with other major risk factors in a transgenic mouse model. Transgenic p53ser246