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A comparison of the pharmacological actions of 4-aminopyridine and two of its derivatives in the monkey

โœ Scribed by Pieter T.M. Biessels; Martin C. Houwertjes; Sandor Agoston; Alan S. Horn

Book ID
115881009
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
372 KB
Volume
135
Category
Article
ISSN
0014-2999

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This research compares the effects, in mice and rats, of desmethylclomipramine (DCLOM) and clomipramine (CLOM). DCLOM antagonized the hypothermia induced in mice by reserpine or apomorphine to a much greater extent than CLOM. Reserpine ptosis in mice was depressed by DCLOM only. Similarly, only DCLO