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A comparison of the mouse bioassay with liquid chromatography–mass spectrometry for the detection of lipophilic toxins in shellfish from Scottish waters

✍ Scribed by E.A. Turrell; L. Stobo

Book ID: 116921804
Publisher: Elsevier Science
Year: 2007
Tongue: English
Weight: 124 KB
Volume: 50
Category: Article
ISSN: 0041-0101
DOI: 10.1016/j.toxicon.2007.04.002

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Since January 1993, neurological symptoms and rapid deaths (5 to 10 min) were typically observed in the mouse bioassay of acetone extracts of digestive glands from Arcachon and Toulon (France) during the winter season. It was assumed initially that a new lipophilic toxin was present because tests us