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A comparison of the endocrine effects of low dose aminoglutethimide with and without hydrocortisone in postmenopausal breast cancer patients

✍ Scribed by Dowsett, M; Harris, A L; Stuart-Harris, R; Hill, M; Cantwell, B M; Smith, I E; Jeffcoate, S L


Book ID
109835665
Publisher
Nature Publishing Group
Year
1985
Tongue
English
Weight
618 KB
Volume
52
Category
Article
ISSN
0007-0920

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The pharmacokinetics of the optical enantiomers of warfarin (R-warfarin and S-warfarin) were investigated in patients treated for breast cancer with aminoglutethimide (AG). The patients received 125 mg AG b.i.d. (i.e., low-dosage regimen); 250 mg AG q.i.d. together with cortisone acetate (i.e. high-