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A Comparison of the Denaturants Urea and Guanidine Hydrochloride on Protein Refolding

โœ Scribed by S.M. West; A.D. Guise; J.B. Chaudhuri

Book ID
115031369
Publisher
Institution of Chemical Engineers
Year
1997
Tongue
English
Weight
255 KB
Volume
75
Category
Article
ISSN
0960-3085

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## Abstract The objective of this study was to address the question of whether or not urea and guanidine hydrochloride (GdnHCl) give the same estimates of the stability of a particular protein. We previously suspected that the estimates of protein stability from GdnHCl and urea denaturation data mi