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A comparison of the acute effects of zotepine and other antipsychotics on rat cortical dopamine release, in vivo

✍ Scribed by H.L. Rowley; P.L. Needham; I.C. Kilpatrick; D.J. Heal

Publisher
Springer-Verlag
Year
2000
Tongue
English
Weight
62 KB
Volume
361
Category
Article
ISSN
0028-1298

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In this study, we report the effects of various typical and atypical antipsychotic drugs (APDs) on the suppressant action of microiontophoretically applied 2-methylserotonin (2-Me-5HT, a 5-HT3 agonist) on medial prefrontal cortical (mPFc) cells. The microiontophoresis of 2-Me-5HT (10-80 nA) produced