A comparison of soft tissue reaction to silastic and absorbable suture material

✍ Scribed by Toranto, I. Richard ;Salyer, Kenneth E. ;Nickell, William B.

• Book ID: 102872786
• Publisher: John Wiley and Sons
• Year: 1974
• Tongue: English
• Weight: 546 KB
• Volume: 8
• Category: Article
• ISSN: 0021-9304
• DOI: 10.1002/jbm.820080313

✦ Synopsis

Abstract

Alloplastic implants in reconstructive surgery have many varied applications. The problem of extrusion in certain areas has not been totally resolved. Our intent was to design and develop a composite alloplastic implant which would be fixed to local tissues by fibrous ingrowth. Small amounts, less than 5% by weight, of a biodegradable substance with either Silicone type A or clear dental acrylic were used. Laboratory rats were implanted subcutaneously with sterile prostheses measuring 21 mm × 1 mm. The biodegradable portion consisted of presently available absorbable suture‐polyglycolic acid, chromic catgut, and plain catgut in small particles. The implants were harvested at six weeks and three months and objectively evaluated for tissue fixation and fibrous reaction. In our model, the composite alloplastic prosthesis of chromic catgut and Silicone type A established superior fixation by fibrous ingrowth with a minimum of fibrous capsular thickness.