This placebo-controlled, randomized, multicenter trial compared the effects of MTX plus UDCA to UDCA alone on the course of primary biliary cirrhosis (PBC). Two hundred and sixty five AMA positive patients without ascites, variceal bleeding, or encephalopathy; a serum bilirubin less than 3 mg/dL; se
โฆ LIBER โฆ
A comparison of S-adenosylmethionine (SAMe), rifampicin (R) and ursodeoxycholic acid (UDCA) in primary biliary cirrhosis (PBC): Interim results
โ Scribed by Bray, GP; Di Padova, C; Tredger, JM; Williams, R
- Book ID
- 122805227
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 63 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0168-8278
No coin nor oath required. For personal study only.
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Ursodeoxycholic acid, a dihydroxyl bile acid normally present in human beings in minimal amounts, becomes incorporated into the bile salt pool when taken orally. In cholestasis, bile acids are retained in the liver and are hepatotoxic. Ursodeoxycholic acid is the least-known hepatotoxic bile acid, h