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A comparison of human H295R and rat R2C cell lines as in vitro screening tools for effects on aromatase

✍ Scribed by Marjoke Heneweer; Martin van den Berg; J.Thomas Sanderson

Book ID
119377728
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
176 KB
Volume
146
Category
Article
ISSN
0378-4274

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## Abstract The adrenal gland is a vulnerable target for toxic insult. Disruption of adrenal steroidogenesis and hormone secretion may cause serious effects on human health. A human __in vitro__ model is needed to predict effects, and elucidate mechanisms of endocrine disruption and adrenal toxicit