A comparison of high frequency switching in the yeastCandida albicans and the slime moldDictyostelium discoideum

Alleviation of experimental hemiparkinso

Alleviation of experimental hemiparkinsonism by high-frequency stimulation of the subthalamic nucleus in primates: A comparison with L-dopa treatment

✍ Abdelhamid Benazzouz; Thomas Boraud; Jean Féger; Pierre Burbaud; Bernard Bioulac 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 551 KB

## Abstract Experimental studies in 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine (MPTP)‐treated monkeys have shown that akinesia and rigidity are linked to a hyperactivity of glutamatergic subthalamic nucleus neurons and that the lesion of this nucleus can ameliorate parkinsonian motor signs. In ou