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A comparison of drug binding sites on mammalian albumins

โœ Scribed by Mohammad R. Panjehshahin; Michael S. Yates; Christopher J. Bowmer


Book ID
115782640
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
813 KB
Volume
44
Category
Article
ISSN
0006-2952

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โœ Yasmina S.N. Day; David G. Myszka ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 254 KB

Surface plasmon resonance-based biosensors can be used to directly measure the binding of small molecules to albumin. We studied 12 drugs with different molecular masses and affinities for albumin to illustrate the benefits of the technology. To examine both high- and low-affinity sites on the prote