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A comparison of DNA-ploidy and karyotype of soft tissue sarcomas

✍ Scribed by E. van den Berg; W.M. Molenaar; B. de Jong; A. Dam; J. Wiersema; A.P. Verstraete


Book ID
119105224
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
91 KB
Volume
52
Category
Article
ISSN
0165-4608

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The most important prognostic factor in soft tissue sarcomas (STS) is tumor grade. Since most grading methods are subject to the interpretation of the individual pathologist, there is a need for objective criteria such as DNA ploidy and karyotype, which are of prognostic value in several types of ma

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## Abstract In soft tissue sarcoma, the prognostic importance of DNA ploidy status is limited. One possible explanation may be technical; small nondiploid stemlines will be diluted in relation to the presence of normal diploid cells and may not be detected by flow cytometry (FCM). We assessed DNA p