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A comparison between oocyte growth in coculture with granulosa cells and oocytes with granulosa cell-oocyte junctional contact maintained in vitro

✍ Scribed by Eppig, John J.


Publisher
John Wiley and Sons
Year
1979
Tongue
English
Weight
364 KB
Volume
209
Category
Article
ISSN
0022-104X

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✦ Synopsis


Abstract

Evidence is presented that strongly supports the hypothesis that the junctional association between oocytes and granulosa cells must be maintained to promote oocyte growth and development in vitro and that the coculture of oocytes with granulosa cells is not a sufficient condition for oocyte development. Furthermore, it is shown that incorporation of uridine and leucine by oocytes into TCA‐insoluble material is significantly greater in granulosa cell‐enclosed oocytes than in cocultured oocytes.


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