A Comparison Between IgG- and IgA-class Antibodies to Cyclic Citrullinated Peptides and to Modified Citrullinated Vimentin in Early Rheumatoid Arthritis and Very Early Arthritis
โ Scribed by SVARD, A.; KASTBOM, A.; SODERLIN, M. K.; RECKNER-OLSSON, A.; SKOGH, T.
- Book ID
- 118035795
- Publisher
- Journal of Rheumatology Publishing Company
- Year
- 2011
- Tongue
- English
- Weight
- 498 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0315-162X
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๐ SIMILAR VOLUMES
## Abstract ## Objective Antiโcyclic citrullinated peptide (antiโCCP) antibodies are rheumatoid arthritis (RA)โspecific serologic markers. RA susceptibility has been associated with HLAโDRB1 shared epitope (SE) alleles and singleโnucleotide polymorphism (SNP) haplotypes in the peptidyl arginine de
## Abstract ## Objective The functional role of HLA class II molecules in the pathogenesis of rheumatoid arthritis (RA) is unclear. HLA class II molecules are involved in the interaction between T and B lymphocytes required for longโlived B cell responses and generation of highโaffinity IgG antibo