A COMPARISON BETWEEN COMPOUND POTENCY IN AN IN VITRO PHOSPHOLIPIDOSIS ASSAY AND AT THE hERG-ENCODED POTASSIUM CHANNEL

Mutational specificities of n-nitrosamin

Mutational specificities of n-nitrosamines in a host-mediated assay: comparison with direct-acting n-nitroso compounds in vitro and an approach to deducing the nature of ultimate mutagens in vivo

✍ Yu-Xin Liu; Joseph B. Guttenplan 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 597 KB

## Abstract The mutational activities and specificities of several __N__‐nitrosamines in __Salmonella__ recovered from mouse liver in the host‐mediated assay (HMA) were compared with the specificities of related direct‐acting __N__‐nitroso compounds in vitro. The specificities of the direct‐acting